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A new way to estimate our maximum lifespan could help us extend it

The maximum lifespan of mammalian species such as humans can be estimated from so-called epigenetic markers - and altering those might extend our longevity

By Michael Le Page

28 November 2023

The maximum age of humans, and other mammalian species, could be predicted from tissue samples

Luke MacGregor/Alamy

We might have found a new way to extend the lifespan of many mammals, including people.

A study of 15,000 tissue samples from 348 mammal species has shown it is possible to predict their maximum lifespan by looking for the presence or absence of labels known as epigenetic markers at specific sites in the genome. What’s more, these could be causal. That is, altering the epigenetic markers might increase maximum lifespans.

“I do think it is quite possible,” says …

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